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28 - 31 AGOSTO 2020

Does it matter what time of day you exercise? - Two teams of researchers analyzing different aspects of exercise in mice found that the time of day might affect the productivity of physical activity.

Scientists already know that the circadian rhythm interacts with our metabolism. A person's circadian rhythm includes physical, mental, and behavioral changes that follow a cycle of 24 hours.
These behavioral patterns develop in response to light and darkness and relate to the circadian clock, which follows the solar time. Circadian rhythms are present in most living things.

Two teams of researchers decided to explore how the time of day can affect the body's response to exercise.
Gad Asher, who works in the Department of Biomolecular Sciences at the Weizmann Institute of Science in Rehovot, Israel, is senior author of the first study, while Paolo Sassone-Corsi of the Center for Epigenetics and Metabolism at the University of California (UC), Irvine, is senior author of the second.

"It's quite well known that almost every aspect of our physiology and metabolism is dictated by the circadian clock," notes Asher.

"Previous studies from our lab have suggested that at least 50% of our metabolism is circadian, and 50% of the metabolites in our body oscillate based on the circadian cycle. It makes sense that exercise would be one of the things that's impacted," says Sassone-Corsi.


Examining mice's response to exercise

The two studies confirm that the circadian rhythm plays an essential role in the way that the body responds to physical movement. Although each team investigated a different component of exercise, the two studies complement each other.

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